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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MDC1 All Species: 8.79
Human Site: T518 Identified Species: 27.62
UniProt: Q14676 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14676 NP_055456.2 2089 226666 T518 E R S Q A S T T V D I N T Q V
Chimpanzee Pan troglodytes Q7YR40 2171 235369 T518 E R S Q A S T T V D I N T Q V
Rhesus Macaque Macaca mulatta Q5TM68 2173 235100 T520 E R S Q A S I T V D I N T Q V
Dog Lupus familis XP_532059 1271 139834
Cat Felis silvestris
Mouse Mus musculus Q5PSV9 1707 184652 P207 E E V S S P A P S V P G P S S
Rat Rattus norvegicus Q5U2M8 1279 136930
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510738 863 91291
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_698304 1913 212679 E413 S S G D L H L E S D T D V E E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.1 88.7 30.1 N.A. 50.3 36.9 N.A. 23.3 N.A. N.A. 21 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 95.4 90.9 41 N.A. 60.4 45.7 N.A. 29 N.A. N.A. 39.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 0 N.A. 6.6 0 N.A. 0 N.A. N.A. 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 0 N.A. 13.3 0 N.A. 0 N.A. N.A. 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 38 0 13 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 13 0 0 0 0 0 50 0 13 0 0 0 % D
% Glu: 50 13 0 0 0 0 0 13 0 0 0 0 0 13 13 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 13 0 0 0 0 0 0 0 0 13 0 0 0 % G
% His: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 13 0 0 0 38 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 13 0 13 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 38 0 0 0 % N
% Pro: 0 0 0 0 0 13 0 13 0 0 13 0 13 0 0 % P
% Gln: 0 0 0 38 0 0 0 0 0 0 0 0 0 38 0 % Q
% Arg: 0 38 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 13 13 38 13 13 38 0 0 25 0 0 0 0 13 13 % S
% Thr: 0 0 0 0 0 0 25 38 0 0 13 0 38 0 0 % T
% Val: 0 0 13 0 0 0 0 0 38 13 0 0 13 0 38 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _